Thromboembolism and antithrombotic therapy in patients with heart failure in sinus rhythm: current status and future directions.
نویسندگان
چکیده
Luca Bettari, Mona Fiuzat, Richard Becker, G. Michael Felker, Marco Metra and Christopher Rhythm: Current Status and Future Directions Thromboembolism and Antithrombotic Therapy in Patients With Heart Failure in Sinus Print ISSN: 1941-3289. Online ISSN: 1941-3297 Copyright © 2011 American Heart Association, Inc. All rights reserved. 75231 is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX Circulation: Heart Failure doi: 10.1161/CIRCHEARTFAILURE.110.959957 2011;4:361-368 Circ Heart Fail. http://circheartfailure.ahajournals.org/content/4/3/361 World Wide Web at: The online version of this article, along with updated information and services, is located on the http://circheartfailure.ahajournals.org/content/4/5/e19.full.pdf An erratum has been published regarding this article. Please see the attached page for:
منابع مشابه
Advances in Heart Failure Thromboembolism and Antithrombotic Therapy in Patients With Heart Failure in Sinus Rhythm Current Status and Future Directions
Heart failure (HF) represents a major and growing public health problem because of its prevalence, incidence, morbidity, mortality, and economic costs. The prevalence of HF is 2% to 3% of the general population.1 Five million Americans are affected, with 550 000 cases diagnosed each year.2 The mortality rate from severe HF remains 60% within 5 years of diagnosis, and 50% of hospitalized patient...
متن کاملAntithrombotic therapy in patients with chronic heart failure: rationale, clinical evidence and practical implications.
Chronic heart failure (CHF) is traditionally associated with increased risk of thromboembolic complications. Key features of CHF pathophysiology, such as impairment of intracardiac hemodynamics, peripheral blood flow deceleration, neuroendocrine activation, chronic oxidative stress and proinflammatory changes, could explain the predisposition to thromboembolism. However, conclusive epidemiologi...
متن کاملAntithrombotic therapy for heart failure in sinus rhythm.
Although the risk of thromboembolism in chronic heart failure is high even in the absence of atrial fibrillation, the risk to benefit ratio of anticoagulation vs. antiplatelet therapy or no antithrombotic therapy is poorly defined in this population. Post hoc analysis of large therapeutic heart failure trials has estimated the risk of thromboembolism to be between 1 and 4.5%. However, most of t...
متن کاملAntiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm: a Cochrane systematic review.
BACKGROUND Heart failure predisposes to stroke and thromboembolism, which in turn contribute to the high mortality and morbidity in heart failure. OBJECTIVES To determine the effect of antiplatelet agents, compared to placebo or anticoagulant therapy, on death and/or major thromboembolic events in adults with heart failure who are in sinus rhythm. DESIGN Systematic review of randomized para...
متن کاملPlatelets and atrial fibrillation.
Atrial fibrillation is the commonest sustained cardiac rhythm abnormality, leading to substantial mortality and morbidity from stroke, thromboembolism and heart failure. Whilst the benefits of antithrombotic therapy in preventing stroke in atrial fibrillation are increasingly recognised, further developments in thromboprophylaxis are needed, especially since warfarin confers the inconvenience o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Circulation. Heart failure
دوره 4 3 شماره
صفحات -
تاریخ انتشار 2011